Chapter 1771 How About... Let Me Try?

Inside the Chencang New Drug Research Institute in the High-tech Development Zone of Dongyang Province.

It has been officially in operation for several months, and everyone is working hard on scientific research, hoping to overcome Parkinson's disease as soon as possible.

After Chen Cang proposed the commonality between Alzheimer's disease and Parkinson's disease, the progress of the entire scientific research work has been greatly improved!

However, scientific research will always give people an illusion!

That is, every breakthrough makes people feel that it is a historic progress, and they all think that they can achieve excellent results.

But the result is... After each breakthrough, I suddenly discovered that the difficulty of this matter is even higher!

To solve problems, the factors and disciplines that need to be considered and learned are still increasing!

Professor Zhang Mu himself is engaged in the research of Alzheimer's disease, so when Chen Cang proposed that the enzyme asparagine endopeptidase can modify the tau protein to make it more viscous and toxic.

Therefore, drugs that inhibit AEP often show certain benefits in the treatment of Alzheimer's disease animal models.

If so, is there an enzyme that increases the toxicity of folded α-synuclein?

This question is really complicated!

It can even be said to be like finding a needle in a haystack.

No one can find an "enzyme" from the complex tissue to explain that this thing can promote the folded pathological α-synuclein?

This requires complex bioengineering to deal with!

There are tense and anxious discussions in the office.

Tidanes frowned and said: "The progress of enzyme engineering is really too slow now, and I have not yet received an accurate answer from Professor Considine!"

"Every time I talk about cooperation, the other party is looking for various reasons to evade."

"Why……"

Hearing that Tidanes was so lost, everyone didn't know how to comfort him.

Considine and Thedanes used to be very good partners.

But since Tidanes came to China, his reputation in a certain circle is like a crooked butt, and everyone has avoided him.

To be honest, scientific research is still divided into national boundaries most of the time.

Even if many people don't want to admit it, they will find various reasons to convince themselves and others.

For example, now, Chen Cang is indeed the person with the fastest research progress in the field of Parkinson's, but why are those powerful experts unwilling to join?

Is it because they are stupid and don't understand?

of course not!

It's not that you are good, everyone will join you.

A very real problem, scientific research is always like a competitive relationship.

As long as you haven't researched the results, no matter how you lead, you can't count as success!

For example, now, experts in the field of enzyme engineering are needed in the institute.

But this top expert is really hard to find.

Few of the former partners of Tedanis are willing to come now!

However, domestic bioengineering itself is in its infancy, and the research on protein enzymes is really stretched.

Even the separation and purification of the simplest enzymes use some biofilm separation technologies decommissioned by the United States five years ago.

These are basic studies!

But these basic researches determine the superstructure.

No scientific research is born out of thin air.

Zhang Mu, as the person in charge, couldn't help but sigh.

The development of domestic medicine is really not just the backwardness of pharmaceutical technology, but because the development of medicine is a comprehensive discipline!

Medicine is not a simple subject, but a sophisticated subject.

It involves physics, chemistry, molecular biology... and many other basic subjects!

Even the separation and purification of enzyme engineering in a small direction is extremely difficult at this moment!

For a while, everyone fell silent.

Yang Lan couldn't help but said, "Why don't we find our old friends from the Chinese Academy of Sciences?"

Zhang Mu shook his head: "His skills are similar to Yu Shuangyong's. You don't need to look for it, and the effect is not obvious."

Upon hearing this, Yu Shuangyong blushed immediately.

Although what Zhang Mu said was not very face-saving, it was the truth!

The breaking and separation of a small enzyme has become a problem to find out the key core!

At this time, the door opened suddenly.

The people who were thinking about it suddenly froze for a moment, they were a little stunned for a moment, and they were even taken aback. For a while, everyone was a little unhappy!

Who's here at meeting time?

Everyone turned around and saw that it was Chen Cang who had come!

Only then did everyone breathe a sigh of relief.

Seeing that the atmosphere was a bit depressed, Chen Cang couldn't help being stunned for a moment: "What's the matter... this is?"

"Is the atmosphere so depressing?"

Everyone sighed when they heard the sound.

And Zhang Mu said directly: "Professor Chen, I just happened to be looking for you, so I sat down and talked."

Chen Cang nodded, found a seat and sat down, looked at Zhang Mu: "What's wrong?"

Zhang Mu said to Yu Shuangyong: "Old Yu, tell me."

Yu Shuangyong nodded and picked up the data in his hand:

"It's like this. We extracted, separated, and purified the enzymes in the nervous system of rats, and we want to conduct research according to Professor Chen's original idea."

"Asparagine endopeptidase can modify the tau protein in Alzheimer's to make it more toxic and adhesive. As you said, Parkinson's is the second most common disease after Alzheimer's disease. Neurodegeneration, we also began to isolate and purify the enzyme in Parkinson's rats."

"But...it seems that we have encountered some problems. I don't know whether it is because of technical reasons or other reasons. In this month, we have conducted more than 600 separations, more than 3,000 inspections, and tens of thousands of tests. There is no enzyme found that makes folded α-synuclein more toxic at all!"

"This is the specific data. There are only 671 enzymes that we can discover now, and we can't go any further!"

After Yu Shuangyong finished speaking, everyone sighed.

Tedanis couldn't help but said: "I went to my friend Professor Considine, but...the other party doesn't seem to be willing to help us!"

Zhang Mu suddenly suggested: "Professor Chen, how about... we change direction?"

Everyone nodded.

Since there is no way to break through the asparagine endopeptidase of Alzheimer's disease in the field of enzymes, maybe we should change the direction?

After all...enzyme engineering is really expensive.

This month, according to Zhang Mu's statistics, nearly 30 million yuan has been invested in this field, but nothing has been achieved, and nothing has been done!

This is scientific research, cruel and realistic!

Just when everyone was a little lost.

Chen Cang suddenly said, "How about... let me try?"

As soon as these words came out, everyone around fell silent.