Chapter 25: Theory of Chinese Patent Medicines
Many compound medicines of Chinese and Western medicines can be said to be the best of both worlds, integrating the strengths of Chinese and Western medicines.
For example, a certain Chinese patent medicine for treating colds has very green and natural ingredients, such as [Sancha Ku], [Gangmei], [Calendula Silver Plate], [Wild Chrysanthemum] (with special emphasis on the word wild), [Acetaminophen], [Chlorobenzene Maleate]...
Hey, it seems like something strange was mixed in.
What is [acetaminophen]? What is [Chlorobenzene Maleate] again?
It turns out that [acetaminophen] is actually paracetamol, which is used to relieve colds and fevers. It inhibits prostaglandin synthase in the hypothalamic temperature-regulating center and causes peripheral blood vessel dilation and sweating through neural regulation to reduce fever.
Chlorpheniramine maleate, also called chlorpheniramine, is an antihistamine that can relieve sneezing and runny nose.
They are all Western medicines used to treat colds and relieve symptoms.
awesome!
The combination of traditional Chinese medicine and western medicine has unlimited power. You can sell the therapeutic effects of western medicine at the price of traditional Chinese medicine.
Cold medicines are considered conscientious, and health supplements are extremely profitable.
For example, a simple vitamin only costs a few yuan for a bottle, but if you change it into a health product and nutritional vitamin tablets, the price can increase more than twenty times. It is really...the password of wealth!
No wonder someone can make a comeback with a [brainless gold]!
Of course, this does not mean that all Chinese patent medicines and traditional Chinese medicines are like this.
Many Western medicines are inspired by the efficacy of Chinese medicine or plants on certain diseases, and the effective main ingredients are extracted from them to make Western medicines.
For example, [chloroquine].
It is said that in 1630, the wife of the Governor of Peru suddenly suffered from an unexplained febrile illness for which there was no cure.
In desperation, I used a bark powder provided by the local Incas for treatment. Unexpectedly, I was miraculously cured. This magical bark was cinchona bark.
Later generations speculated that the governor's wife was suffering from malaria, and cinchona was also called the "tree of life" by the locals.
In 1820, Swedish scientists were inspired by the use of cinchona bark to treat malaria. After repeated experiments, they extracted an active ingredient from the bark and named it "quinine." Quinine means bark in Peruvian.
But malaria was prevalent in those years, and there were many patients. The quinine extracted from the bark of the tree could not be tolerated by the tree or humans. Only the royal family, princes and nobles were eligible to enjoy the extracted quinine. Common people could not even think about it. promotion.
In 1934, German scientists artificially synthesized a chemical drug named chloroquine based on quinine's active ingredient "quinoline" and mass-produced it. Chloroquine is more effective than quinine and has fewer side effects. The key is that it can be produced in large quantities and can be popularized by the public.
In 1944, scientists synthesized a newer antimalarial drug, hydroxychloroquine, based on chloroquine. The difference between hydroxychloroquine and chloroquine is that a hydroxyethyl group replaces an ethyl group in chloroquine. It is precisely because of this small difference that hydroxychloroquine is absorbed faster in the human gastrointestinal tract and distributed wider in the body. More importantly, not only is the efficacy not reduced, but the side effects are halved.
Of course, science is always improving.
Later, better drugs became available. Chinese scientist Tu Aao led a team to extract artemisinin from the traditional Chinese medicine Qinghao, which has better effects and lower side effects.
In addition to [chloroquine], there are many Western medicines extracted from plants.
For example, [salicylic acid], which has anti-inflammatory effects, was studied from the therapeutic effects of willow bark.
The British clergyman Edward Stone dried willow bark, then ground it into powder and gave it to patients with cold and fever. He found that the patient's cold and fever symptoms had significantly subsided, and when the dose was increased, the cold and fever symptoms even disappeared. He gave willow bark powder to 50 patients and found it to be very safe and effective.
Later scientists studied this and finally discovered [salicylic acid].
Taxol, which can treat cancer, is also a compound extracted from the yew plant.
Because its molecular structure is very complex and difficult to synthesize artificially, the price of [Paclitaxel] is also very high.
These are not listed for now.
He Youman felt that there must be some kind of organic compound in [Golden Scale Grass], which would produce a magical chemical reaction with certain ingredients in a series of Chinese medicines in the formula, which would lead to such an amazing effect.
【Golden scale grass】taken alone will not have this effect.
It's just that the ingredients of the various medicinal materials involved are too complex, and He Youman can't study them for a while. Unless there is a large research team to assist her, it is possible to discover something in a short time.
For now, He Youman is still conducting research through proprietary Chinese medicine formulas.
With the assistance of the [Four-Armed King Kong]'s auxiliary ability that far exceeds the ordinary [Super Computing], He Youman's research speed is very fast.
This is how the new drug with the ingredient [Viagra] was added.
He Youman said calmly, "To put it simply, it can make [Viagra] more effective and more effective. Moreover, it is a one-time drug. It is not like the previous versions of the drug." , permanently changing the physical condition by taking medicine for a long time. Of course, [Viagra] also has the side effects that it should have, and there may be other side effects, but the current experimental time is too short, the experimenters are too few, and no abnormalities have been found. .”
In order to satisfy He Youman's experiment, Li Dongsheng called all his younger brothers over.
But He Youman felt that it was still a bit insufficient.
For this reason, she had previously reported to Wu Siyuan in the United States, requesting that Li Dongsheng, the leader of Jimen, be strengthened.
Without saying a word, Wu Siyuan gave Li Dongsheng US$2 million [development] through Hong Kong channels!
I am more grateful than Li Dongsheng!
The resentment towards Wu Siyuan deep in my heart disappeared. Of course, the fear of Wu Siyuan was even higher.
In Hong Kong's "Young and Dangerous" movie, the East Star boss Luo Tuo also said that if someone is rich, just throw away a few million and buy a killer, and you will have to run for your life.
When He Youman said that the effect of the medicine was not permanent, Wu Siyuan was moved.
Honestly, for a drug, what kind of situation does a businessman think is best?
That is the kind that has an immediate effect on a certain disease, but cannot be eradicated and can only be treated with long-term medication.
Obviously, the drug developed by He Youman combined with [sildenafil] has such an effect.
However, the side effects of the drug need to be further clarified.
Wu Siyuan told He Youman this point, and He Youman nodded and said that he would strengthen his observations in this area.
However, she added that in order to obtain accurate and effective data, large-scale clinical trials must be conducted.
And if she wants to speed up her research, she also needs the assistance of a capable research team.
After all, there are some jobs that [Four-Armed King Kong] cannot replace.
Wu Siyuan nodded, indicating that he understood.